Can You Develop a CBD Tolerance?

|Lisa Strange
Can You Develop a CBD Tolerance

Using CBD regularly might make you question if your body can build a tolerance, reducing its effects over time.

As more people turn to CBD for its potential to support relaxation, sleep, and overall well-being, understanding how it interacts with your body is essential.

This is especially important for those who use CBD daily or are considering long-term use.

This article will examine whether you can build a tolerance to CBD oil, what the science says, and how to manage your usage to maintain its benefits. 

Read on to learn how CBD works in your system and what to expect with consistent use.

Can You Build a Tolerance to CBD Oil?

You cannot build up a tolerance to CBD oil. The opposite is much more likely to be true.

You can build up a reverse tolerance to CBD, which means you need less over time to get the desired effect.

As CBD is a cannabinoid, the same as THC, it would be natural to assume it has many of the same tendencies, including building a tolerance.

The truth is that CBD and THC share a few traits (they both affect the endocannabinoid system, for example), but they are, in fact, very different in other ways.

There are significant differences between CBD and THC.

CBD has become very popular for treating anxiety, which THC is known to trigger.

CBD also doesn’t trigger psychoactivity, which THC infamously does.

Another significant difference between the two is the risk of tolerance.

The main issue with THC is that there is a slow increase in tolerance levels when used for medicinal or recreational purposes.

The initial dose will eventually become ineffective when taken regularly.

Consuming CBD oil does not create tolerance. Oddly enough, it seems to have the opposite effect.

A much less well-known phenomenon is called reverse tolerance.

Are you interested in experiencing the potential benefits of CBD oil for yourself? Check out our Full Spectrum CBD oil here.

How Does Tolerance Develop in the First Place?

Tolerance develops most commonly with drugs that bind directly to our endocannabinoid receptors (THC being an example).

Long-term use leads to an internal response from the endocannabinoid system, and our bodies adapt to the compound’s continual presence.

As such, a higher dosage is required to achieve the same effect.

Research has shown that long-term THC use leads to increased tolerance.

THC binds strongly to the cannabinoid receptor CB1, responsible for the psychoactive effect.

Over time, THC reduces the number of available cannabinoid receptors.

This was supported by a study conducted in 2012, which showed that chronic THC users had fewer cannabinoid receptors than non-users.

After a break from THC, the same users returned to lower dosages, and their cannabinoid receptor levels returned to normal. 

NOTE – You might also enjoy reading this post about CBD withdrawal symptoms.

How Does CBD Reverse Tolerance Occur?

As the name suggests, CBD reverse tolerance is the opposite of tolerance to CBD.

Continued substance use reduces tolerance, and the user needs less substance to achieve the desired effect.

Most substances cause people to experience increased tolerance levels – everything from pharmaceuticals, nicotine, alcohol, and hard drugs like cocaine and methamphetamine.

In some rare cases with alcohol, the opposite is experienced due to severe liver damage.

There are limited studies on the tolerance of CBD, but the consensus is that there is little to no risk of developing a tolerance.

This is because CBD does not technically bind to any single cannabinoid receptor, eliminating the tolerance problem.

CBD promotes increased receptor activity, unlike THC, which reduces cannabinoid receptors over time.

Other receptors, such as GABA and NMDA receptors, also respond to CBD and have been shown to contribute to reverse tolerance. 

Whatever the reason for CBD oil’s reverse tolerance, consumers can gradually reduce their dosage over time.

Note—You may also find this article, which examines the pros and cons of CBD oil, useful.

Personal Anecdotes About CBD Oil Tolerance

Some personal reports are online where people claim to have experienced CBD tolerance when taking it for anxiety. 

However, on closer inspection, some of these complaints stemmed from users struggling to find a high-quality source of CBD oil. 

There is, however, something to be aware of called CBD saturation. This is often found in users taking CBD oil for epilepsy.

After long-term CBD use, users may begin to experience seizures again.

Common sense would suggest a higher dosage may be needed at that point, but evidence suggests the opposite: a lower dose or a break from CBD oil could help restore its effectiveness.

The truth is that more research needs to be conducted about tolerance to CBD oil. However, in the meantime, users have been able to find their solutions with excellent results.

Final Notes On if You Can Build a Tolerance to CBD Oil

Building a tolerance to CBD oil is impossible due to how it interacts with the body.

The opposite is true; over time, a reverse tolerance may occur with regular consumption, where less CBD is needed to garner the same effects.

So, to conclude, CBD tolerance is nothing to worry about.

Especially if you use high-quality CBD oil, you are unlikely to experience any tolerance to CBD.

That is the end of this post, looking at the question: can you build a tolerance to CBD oil?